Remifentanil induced hyperalgesia

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August undefined, 2024

WebOpioids are a mainstay of acute pain management but can have many adverse effects, contributing to problematic long-term use. Opioid tolerance (increased dose needed for analgesia) and opioid-induced hyperalgesia (paradoxical increase in pain with opioid administration) can contribute to both poorly controlled pain and dose escalation. … http://yuxiqbs.cqvip.com/Qikan/Article/Detail?id=7106300610

Remifentanil-induced postoperative hyperalgesia and its …

WebAug 31, 2024 · Our research group has been committed to the research of remifentanil-induced hyperalgesia for a long time. In the previous study, it was found that intraoperative infusion of remifentanil (0.3ug/kg•min) >1h can lead to remifentanil-induced hyperalgesia and the incidence rate is relative high in the plain area. WebFu R et al. P2X4 receptor in the dorsal horn contributes to BDNF/TrkB and AMPA receptor activation in the pathogenesis of remifentanil-induced postoperative hyperalgesia in rats. Neurosci Lett 750:135773 (2024). PubMed: 33639220 british ambassador in paris

Hyperalgesia: Causes, types, and treatment - Medical News Today

WebOpioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids such as morphine, oxycodone, and methadone. OIH is not necessarily confined to the original affected site. This means that if the person was … WebRemifentanil-induced hyperalgesia was defined as a decrease in pain thresholds measured before the start and after the discontinuation of the remifentanil infusion (S1 and S5, … can you use hydrogen peroxide for ear ache

Full article: Remifentanil-induced postoperative hyperalgesia: …

Remifentanil-induced Postoperative Hyperalgesia and Its …

WebDec 15, 2024 · Remifentanil-induced hyperalgesia (RIH) is a severe but common postoperative clinical problem with elusive underlying neural mechanisms. Here, we discovered that glutamatergic neurons in the thalamic ventral posterolateral nucleus (VPLGlu) exhibited significantly elevated burst firing accompanied by upregulation of … WebTo evaluate the relationship between NR2B subunit-containing N-methyl-D-aspartate (NMDA) receptors (NR2B receptors) and Ca 2+ /calmodulin-dependent protein kinase Ⅱ α (CaMKⅡα) in the spinal cord during remifentanil-induced hyperalgesia in a rat model of incisional pain (IP). can you use hydrogen peroxide on seedlingsWebObjective To compare the effect of Sufentanil and Remifentanil in emergency operation of traumatic brain injury.Method From January 2024 to December 2024,80 patients with traumatic brain injury admitted to the emergency department of the 990th Hospital of PLA Joint Logistics Support Force were divided into control group(40 cases)and observation … british ambassador the hague

"WebOct 8, 2012 · Therefore, it is of interest to investigate other ways of preventing opioid-induced hyperalgesia. In a recent animal study it has been shown that gradual dose … " - Remifentanil induced hyperalgesia

Remifentanil induced hyperalgesia

WebWe therefore compared the time course of analgesic and antihyperalgesic effects of the intravenous COX-2 inhibitor parecoxib on remifentanil, a short-acting μ-receptor agonist, … WebElectro-acupuncture Treatment Alleviates the Remifentanil-induced Hyperalgesia by Regulating the Activities of Ventral Posterior Lateral Nucleus of the Thalamus Neurons in Rats. Neural Plasticity 2024 ... The induction of long-term potentiation in spinal dorsal horn after peripheral nociceptive stimulation and contribution of spinal TRPV1 in ...

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WebMar 30, 2024 · Liu Q, Wu X, Guo J, Gao J, Liu B, Wang Y, Xia M, Pei L, Sun J. Analgesic Effect of Electroacupuncture on Postherpetic Neuralgia: A Trial Protocol for a Multicenter Randomized Controlled Trial. Pain Ther. 2024 Dec;10(2):1755-1771. doi: 10.1007/s40122-021-00283-8. Epub 2024 Jul 12. WebTo investigate the changes in the expression of Ca 2+ /calmodulin-dependent protein kinaseⅡα(CaMKⅡα)in the spinal cord and dorsal root ganglia(DRG) during remifentanil-induced hyperalgesia in a rat model of incisional pain(IP).

WebDec 28, 2024 · Remifentanil is the opioid most convincingly associated with OIH, and hereby we provide a review of remifentanil-induced hyperalgesia, describing both the underlying … WebApr 12, 2024 · Spinal peroxynitrite contributes to remifentanil-induced postoperative hyperalgesia via enhancement of divalent metal transporter 1 without iron-responsive element-mediated iron accumulation in rats Anesthesiology , 122 ( 4 ) ( 2015 ) , pp. 908 - 920

WebSep 9, 2016 · In conclusion, hydrogen-rich saline (10ml/kg) might reverse remifentanil-induced hyperalgesia, through regulating NR2B-containing NMDAR trafficking to control MnSOD nitration and enhance MnSOD ... WebOpioids have dominated the management of perioperative pain in recent decades with higher doses than ever before used in some circumstances. Through the expanding use of opioids, growing research has highlighted their associated side-effects and the intertwined phenomena of acute withdrawal syndrome, opioid tolerance, and opioid-induced …

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WebEffect of continuous infusion of dexmedetomidine on hyperalgesia during recovery period of remifentanil anesthesia during thoracotomy lobectomy 导出摘要目的:观察在创伤较大的开胸肺叶切除术中持续输注小剂量的右美托咪定,对大剂量使用瑞芬太尼麻醉苏醒期痛觉过敏的 … can you use hydrogen peroxide orally dailyWebIntroduction. Clinical and experimental research indicates that severe postoperative pain after the intraoperative use of remifentanil (Remi) has been linked to the development of … british ambassadors to usaWebBackground: Experimental studies and clinical observations suggest a possible role for opioids to induce pain and hyperalgesia on withdrawal. The authors used a new … british ambassador to italyWebIntroduction: Therapeutic opioid use continues to grow, with greater than a fivefold increase in usage of fentanyl-based products over a 10-year period. Opioids are known for their … british ambassador to greeceWebGlobal-to-Local Neural Networks for Document-Level Relation Extraction, EMNLP 2024 - GLRE/word2id.json at master · nju-websoft/GLRE british ambassador office to usaWebOct 1, 2004 · Abstract Background and aim: Several animal and human studies have proposed that acute tolerance to opioids might be manipulated by NMDA receptor antagonists. This study was designed to test the opioid-induced hyperalgesia produced by remifentanil, and to evaluate the effect of ketamine under these conditions. Methods: … can you use hyphen in email addressWebthe risk of remifentanil-induced hyperalgesia (RIH), from the avoidance of high doses of remifentanil to the implementation of drugs specifically targeting the mechanisms of … can you use hydro seal bandages for acne